Ozone Therapy

Ozone, a natural gas formed in the atmosphere, acts as a vital UV filter and has medical uses. Unlike breathable O2, ozone (O3) consists of three oxygen molecules. Medicinal Ozone therapy employs a generator that mixes oxygen and ozone by passing oxygen through a discharge, creating an ozone-rich gas. Concentration and dosages vary for individualized treatment. Ozone triggers therapeutic chemical changes on contact, serving as an adjuvant treatment for various diseases, an anti-aging remedy, and a performance enhancer for athletes, promoting overall well-being.

"They are the BEST. They have treated many body parts of mine for the last 10 years. Would not go anywhere else. They have everything here from PT, cupping, E- Stem, chiropractor, Stem Cells, peptides, PRP, vitamin IVs, anything for keeping yourself healthy!"

-Sherry Ireland

"Outstanding therapists and support staff, in an immaculate office. Overall phenomenal experience, and great results."

-Matt H

How can we help you?

Ozone is a highly oxidative and reactive gas that is considered as a stressor pro-drug to your body (a). At therapeutic concentrations, Medical Ozone can can promote various physiological effects.

How Does Ozone Therapy Work?

Modulate your Immune System
Activate your own antioxidant mechanisms
Oxygenate your tissues
Activate your metabolism
Activate circulation
Reduce inflammation in your body
Increase energy production
Induce the secretion of substances like endorphins, serotonin, and other neurotransmitters

The potential benefits of Medical Ozone Therapy and the science behind it

Germicidal– Ozone has been found to have direct killing effects on viruses, fungi, and bacteria in the body (a,b,c).
Anti-inflammatory – Ozone inhibits pro-inflammatory pathways in the body (d,e,f,i,j)
Improved Oxygen metabolism – Ozone helps shift the oxygen-hemoglobin dissociation curve, allowing red blood cells to release oxygen more efficiently to tissues low in Oxygen content. It also aids in red blood cell metabolism, elasticity, and blood flow. There is a significant improvement in blood flow and oxygenation of ischemic tissues due to ozone treatment (g,h).
Antioxidant – Ozone activates your body’s own antioxidant mechanisms (k)
Immune Boosting – Ozone works through many different pathways to boost your body’s immune responses (d,e,k).

What can Ozone Therapy Treat?

Ozone therapy and dosing is individualized to the patient. Depending on the condition treated, there are numerous routes and protocols to enable the patient back to their desired activity level. These options will be discussed at your consultation with Dr. Poovendran to establish the most effective treatment for you.

Illness – Through its many biological functions, Ozone can help a patient recover more quickly from viral infections, bacterial infections, and fungal infections. It does this by augmenting your immune system as well as killing pathogens directly.
Sports recovery – Through anti-inflammatory effects, oxygen delivery effects, and immune-boosting effects, Ozone therapy can help you during all phases of your training program, making workouts more effective, and recovery quicker.
Anti-Aging – Through anti-oxidant, oxygen delivery, and metabolic effects, Ozone therapy can help improve the quality of life in patients by making them feel better and more energetic
Health Maintenance – As part of a wellness routine, ozone therapy can be utilized to help patients feel more energetic, more alert, recover from activity faster, and fight off infections.
Arthritis Pain – Through anti-inflammatory effects as well as analgesic effects, ozone use has been shown to help patients with joint pain.

Studies show improved pain relief, at least for the first 6 months when compared to cortisone injection – a safer alternative to a cortisone injection.e

Frequently Asked Questions

How is Ozone Therapy Performed?

At USA Sports Medicine, we use Medical Ozone in several different modalities. Ozone can be injected directly into the tissue to facilitate healing and decrease pain.

We can combine it with Platelet Rich Plasma (PRP) Injections to augment its effects.

In other situations, it can be used in conjunction with a prolotherapy solution to decrease inflammation or facilitate healing (Prolozone).

Also, we perform major autohemotherapy, a powerful systemic treatment, where ozone is given intravenously (through an IV) after being mixed with the patient’s blood.

References

Smith NL, Wilson AL, Gandhi J, Vatsia S, Khan SA. Ozone therapy: an overview of pharmacodynamics, current research, and clinical utility. Med Gas Res. 2017;7(3):212-219.
Elvis AM, Ekta JS. Ozone therapy: A clinical review. J Nat Sci Biol Med. 2011;2(1):66-70. doi:10.4103/0976-9668.82319
Wentworth P Jr, McDunn JE, Wentworth AD, et al. Evidence for antibody-catalyzed ozone formation in bacterial killing and inflammation. Science. 2002;298(5601):2195–2199
Re L, Martinez-Sanchez G, Bordicchia M, et al. Is ozone pre-conditioning effect linked to Nrf2/EpRE activation pathway in vivo? A preliminary result. Eur J Pharmacol. Nov 5 2014;742:158-162.
Bocci V, Valacchi G. Nrf2 activation as target to implement therapeutic treatments. Front Chem 2015;3:4. Doi: 10.3389/fchem.2015.00004
Ricevuti, G. Oxygen-ozone immunoceutical therapy in COVID-19 outbreak: facts and figures, [Ozone Therapy 2020; 5:9014]
Sagai M, Bocci V. Mechanisms of action involved in ozone therapy: is healing induced via a mild oxidative stress? Med Gas Res 2011;1:29.
Hernández F, Calunga JL, Turrent J, Menéndez S and Montenegro A. Ozone therapy effects on blood biomarkers and lung function of asthma patients. Arch Med Res 2005;36(5):549-554.
Pecorelli A, Bocci V, Acquaviva A, Belmonte G, Gardi C, Virgili F, Ciccoli L, Valacchi G. NRF2 activation is involved in ozonated human serum upregulation of HO-1 in endothelial cells. Toxicol Appl Pharmacol 2013;267:30-40.
Schulz S, Ninke S, Watzer B, Nusing RM. Ozone induces synthesis of systemic prostacyclin by cyclooxygenase-2 dependent mechanism in vivo. Biochem Pharmacol 2012;83:506–513.
Bocci V, Aldinucci C, Mosci F; Carraro F; Valacchi G. Ozonation of human blood induces a remarkable upregulation of heme oxygenase-1 and heat stress protein-70. Mediators Inflamm 2007;2007:26785.

Where is this service offered?

Find Your Pain Solution

Herniated Disc
Radiculopathy
Facet Joint Dysfunction
Stenosis
Muscle Stiffness/Tightness
Headaches
Sacro-Iliac Joint Pain (SIJ)
Nerve Entrapment
Back Pain
Neck Pain
Post-Surgical Care

Shoulder Pain
Rotator Cuff Tear/Sprain
Biceps Tendonitis
Shoulder Labral Tear
Shoulder
Impingement/Bursitis
Adhesive Capsulitis/Frozen
Shoulder
Scapular Dyskinesia
AC Joint Separation
Stenosis
Post-Surgical Care

Lateral Epicondylitis (Tennis Elbow)
Medial Epicondylitis (Golfer’s Elbow)
Climber’s Fracture
Trigger Finger
Wrist Sprain
Wrist Fractures

Knee Pain
Total Knee Replacement
ACL Sprain/Tear
MCL Sprain/Tear
PCL Sprain/Tear
Meniscus Tear
Osteoarthritis
Osgood Schlatter’s
Jumper’s Knee
Patello-Femoral Pain
Syndrome
IT Band Syndrome
Hamstring Strain
Osgood Schlatter’s
Quadriceps Strain
Baker’s Cyst

Osteoarthritis
Total Hip Replacement
Femoral-Acetabular
Impingement (FAI)
Piriformis Syndrome
Hip Trochanteric Bursitis
Gluteus Medius Tear
Nerve Entrapment
Hip Labral Tear
Stenosis
Post-Surgical Care

Shin Splints
Ankle Sprains
Plantar Fasciitis
Heel Spur
Turf Toe
Bunions
Falls
Achilles Tendonitis
Parkinson’s
Stroke

Ozone Therapy

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Frequently Asked Questions

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