Peptide Therapy

What are Peptides?

You may not be familiar with the word peptides.  Peptides are short chains of amino acids, the building blocks for proteins, that exert distinct effects in the body.  Peptides are found in every cell and tissue in the human body and play a key role in skin health, muscle health, weight management, and much more. Peptides are essential when it comes to achieving homeostasis and overall good health.  Fortunately, peptides are found in many of the products we already use like skin creams and many of the foods we consume like almonds, eggs, fish, and meat. Peptides are also commonly used in dietary supplements like BCAAs and whey protein.  

Some peptides work like neurotransmitters, some like hormones, while others directly interact with the body’s response to an activity. Essentially, they act as messengers used to send messages from one tissue to another.  Our bodies can efficiently process them, allowing for minimal side effects.

Thanks to their favorable safety profile, we can comfortably use them as a preventive measure to combat the signs of aging. Peptide therapy is used for weight loss, tissue healing, muscle growth, hair growth, fat burning, and sexual wellness. Peptide therapy may also improve cognitive function and sleeping patterns.

 

What is Peptide Therapy?

Peptide therapy is a newly emerging science that helps to achieve different types of body transitions, both internal and external. The goal of peptide therapy is to elevate low peptide levels that cannot be restored by consuming whole foods that contain them or by taking supplements. Peptide therapy is the deliberate and targeted use of peptides as a means of triggering a specific reaction in the human body.

Since peptides vary in design and number, effects vary as well.  Our approach to peptide therapy is individualized to the needs of the patient, as each peptide has different functions. Some peptides, for example, are used to help reduce pain and inflammation while others might be used to break down visceral fat for those who are overweight. Also, growth hormone-releasing peptides can be used to help patients build long, lean muscles.

 

How is Peptide Therapy Administered? 

Typically, peptides are administered through small injections into the skin.  This allows them to efficiently get into the bloodstream without being changed by metabolism and breakdown that occurs in the stomach and GI tract. However, there are also specially formulated oral capsules, lozenges, lotions, creams, and nasal sprays which can be used for some specific conditions.  

All in all, peptide therapy can be used to treat a myriad of health problems. And regardless of the methodology or the condition that precipitates the need for them, peptides function as short linear chains of amino acids that help facilitate the signaling of molecules for biological pathways.

 

When Can You Expect to See Benefits?

Consistency in treatment is the key.  Peptide therapy acts as a support system to improve the progress of specific issues and may help reverse some of these issues.   It may take several weeks or months before you notice a true difference.   

At USA Sports Medicine, we utilize a variety of peptides to help you achieve your health and wellness goals.

 

BPC-157: Body Protection Complex

BPC-157 is a peptide referred to as the “Wolverine” supplement because of its amazing healing capabilities.  It was originally isolated from gastric secretions, and can be taken as an injectable or oral, depending on the condition we are treating.

Potential Benefits of BPC-157 include: increased speed of tissue healing, decreased post-workout soreness, gut protection and repair, reduced oxidative stress, promotes tendon and joint health, and accelerates bone healing.

 

CJC-1295

CJC-1295, taken as an injectable, is a type of Growth Hormone Releasing Hormone (GHRH) which stimulates your body’s own release of growth hormone.  It has the added benefit that it does not increase the release of other hormones such as prolactin, cortisol, or aldosterone that other GHRH peptides can release.  This means less side effects.

CJC-1295  This is a great option for those who are looking to promote a steady and improved release of Growth Hormone.

Potential Benefits of CJC-1295 include: decreased body fat, increased muscle mass, improved tissue repair, improved energy and strength, improved sleep quality, improved bone density, improved immune function, improved fat burning, improved skin elasticity, enhanced mental and physical performance

 

Ipamorelin

Ipamorelin, taken as an injectable, is a type of Growth Hormone Secretagogue Peptide (GHP) which stimulates the production of growth hormone in your body.  With virtually no side effects, it is one of the safest, most effective forms of growth hormone (GH) restoration.  

It is widely used in protocols for age management, disease management, sports performance (in amateur athletes), and injury recovery.

Potential Benefits of Ipamorelin include: decreased body fat, increased muscle mass, improved tissue repair, improved energy and strength, improved sleep quality, improved bone density, improved immune function, improved fat burning, improved skin elasticity, enhanced mental and physical performance

 

5-Amino-1MQ

5-Amino-1MQ, taken orally, is an inhibitor of nicotinamide N-methyltransferase (NNMT).  Too much NNMT is associated with increased body fat and other disease processes.  It does not interfere with any other enzymes in the body, therefore the risk of side effects is very low.

Use of 5-Amino-1MQ was shown to decrease body fat percentage and cholesterol levels by 30% in some studies, as well as a decrease in total body weight by 6%.

Potential Benefits of 5-Amino-1MQ include: Fat Loss, Increased Muscle Mass/Power, Decreased Insulin Resistance, Decreased Muscle Soreness After Workouts, Increased Energy Levels, Decreased Cholesterol Levels

 

Semax

Semax, a nasal spray, is a melanocortin peptide that affects learning and exploratory behavior, accelerates nerve regeneration, and improves neuromuscular performance.  There are no reported side effects of taking this peptide.  

This class of peptides control many behaviors such as regulating attention, processes of learning, and memory formation as a result of their pronounced effect on CNS functions.

Potential benefits of Semax include: Improved Mental Focus and Clarity, Improved Memory Formation and Retention, Nerve Regeneration, Neuroprotection

 

Semaglutide

Semaglutade, is a GLP-1 antagonist, which is designed for increased blood sugar control when combined with diet and exercise.  Side effects of this medication are rare and include nausea which resolves with continued treatment.

Treatment with Semaglutide has resulted in significant weight loss, with 50% of patients noting a loss of 15% or more of their body weight.

Potential benefits of Semaglutide include: weight loss, improved glycemic control, decreased cardiovascular disease.

 

Find Your Pain Solution

  • Spine
  • Shoulder
  • Elbow/Wrist/Hand
  • Herniated Disc
  • Radiculopathy
  • Facet Joint Dysfunction
  • Stenosis
  • Muscle Stiffness/Tightness Headaches
  • Sacro-Iliac Joint Pain (SIJ)
  • Nerve Entrapment
  • Back Pain
  • Neck Pain
  • Post-Surgical Care
  • Shoulder Pain
  • Rotator Cuff Tear/Sprain
  • Biceps Tendonitis
  • Shoulder Labral Tear
  • Shoulder Impingement/Bursitis
  • Adhesive Capsulitis/Frozen Shoulder
  • Scapular Dyskinesia
  • AC Joint Separation
  • Stenosis
  • Post-Surgical Care
  • Lateral Epicondylitis (Tennis Elbow)
  • Medial Epicondylitis (Golfer’s Elbow)
  • Climber’s Fracture
  • Trigger Finger
  • Wrist Sprain
  • Wrist Fractures
  • Knee
  • Hip
  • Ankle/Foot/Balance
  • Knee Pain
  • Total Knee Replacement
  • ACL Sprain/Tear
  • MCL Sprain/Tear
  • PCL Sprain/Tear
  • Meniscus Tear
  • Osteoarthritis
  • Osgood Schlatter’s
  • Jumper’s Knee
  • Patello-Femoral Pain Syndrome
  • IT Band Syndrome
  • Hamstring Strain
  • Osgood Schlatter’s
  • Quadriceps Strain
  • Baker’s Cyst
  • Osteoarthritis
  • Total Hip Replacement
  • Femoral-Acetabular Impingement (FAI)
  • Piriformis Syndrome
  • Hip Trochanteric Bursitis
  • Gluteus Medius Tear
  • Nerve Entrapment
  • Hip Labral Tear
  • Stenosis
  • Post-Surgical Care
  • Shin Splints
  • Ankle Sprains
  • Plantar Fasciitis
  • Heel Spur
  • Turf Toe
  • Bunions
  • Falls
  • Achilles Tendonitis
  • Parkinson’s
  • Stroke
  • Spine
  • Herniated Disc
  • Radiculopathy
  • Facet Joint Dysfunction
  • Stenosis
  • Muscle Stiffness/Tightness Headaches
  • Sacro-Iliac Joint Pain (SIJ)
  • Nerve Entrapment
  • Back Pain
  • Neck Pain
  • Post-Surgical Care
  • Shoulder
  • Shoulder Pain
  • Rotator Cuff Tear/Sprain
  • Biceps Tendonitis
  • Shoulder Labral Tear
  • Shoulder Impingement/Bursitis
  • Adhesive Capsulitis/Frozen Shoulder
  • Scapular Dyskinesia
  • AC Joint Separation
  • Stenosis
  • Post-Surgical Care
  • Ankle/Foot/Balance
  • Shin Splints
  • Ankle Sprains
  • Plantar Fasciitis
  • Heel Spur
  • Turf Toe
  • Bunions
  • Falls
  • Achilles Tendonitis
  • Parkinson’s
  • Stroke
  • Elbow/Wrist/Hand
  • Lateral Epicondylitis (Tennis Elbow)
  • Medial Epicondylitis (Golfer’s Elbow)
  • Climber’s Fracture
  • Trigger Finger
  • Wrist Sprain
  • Wrist Fractures
  • Knee
  • Knee Pain
  • Total Knee Replacement
  • ACL Sprain/Tear
  • MCL Sprain/Tear
  • PCL Sprain/Tear
  • Meniscus Tear
  • Osteoarthritis
  • Osgood Schlatter’s
  • Jumper’s Knee
  • Patello-Femoral Pain Syndrome
  • IT Band Syndrome
  • Hamstring Strain
  • Osgood Schlatter’s
  • Quadriceps Strain
  • Baker’s Cyst
  • Hip
  • Osteoarthritis
  • Total Hip Replacement
  • Femoral-Acetabular Impingement (FAI)
  • Piriformis Syndrome
  • Hip Trochanteric Bursitis
  • Gluteus Medius Tear
  • Nerve Entrapment
  • Hip Labral Tear
  • Stenosis
  • Post-Surgical Care

Schedule a Consultation with a USA Sports Therapy Specialist Today

Citations

  • Studies Cited:
  • 1. Hernigou P, Bouthors C, Bastard C, Flouzat Lachaniette CH, Rouard H, Dubory A. Subchondral bone or intra-articular injection of bone marrow concentrate mesenchymal stem cells in bilateral knee osteoarthritis: what better postpone knee arthroplasty at fifteen years? A randomized study. Int Orthop. 2021 Feb;45(2):391-399. doi: 10.1007/s00264-020-04687-7. Epub 2020 Jul 2. PMID: 32617651.
  • 2.Prodromos, Chadwick & Finkle, Susan. (2020). Autologous Biologic Treatment with Fat, Bone Marrow Aspirate and Platelet Rich Plasma Is an Effective Alternative to Total Knee Arthroplasty for Patients with Moderate Knee Arthrosis. Medicines. 7. 37. 10.3390/medicines7060037.
  • 3. Y.S. Kim, Y.J. Choi, S.W. Lee, O.R. Kwon, D.S. Suh, D.B. Heo, Y.G. Koh. Assessment of clinical and MRI outcomes after mesenchymal stem cell implantation in patients with knee osteoarthritis: a prospective study, Osteoarthritis and Cartilage, Volume 24, Issue 2, 2016, Pages 237-245, ISSN 1063-4584, https://doi.org/10.1016/j.joca.2015.08.009.
  • 4. Vangsness CT Jr, Farr J 2nd, Boyd J, Dellaero DT, Mills CR, LeRoux-Williams M. Adult human mesenchymal stem cells delivered via intra-articular injection to the knee following partial medial meniscectomy: a randomized, double-blind, controlled study. J Bone Joint Surg Am. 2014 Jan 15;96(2):90-8. doi: 10.2106/JBJS.M.00058. PMID: 24430407.
  • 5. Hernigou P, Flouzat Lachaniette CH, Delambre J, Zilber S, Duffiet P, Chevallier N, Rouard H. Biologic augmentation of rotator cuff repair with mesenchymal stem cells during arthroscopy improves healing and prevents further tears: a case-controlled study. Int Orthop. 2014 Sep;38(9):1811-8. doi: 10.1007/s00264-014-2391-1. Epub 2014 Jun 7. PMID: 24913770.
  • 6. Centeno C, Fausel Z, Stemper I, Azuike U, Dodson E. A Randomized Controlled Trial of the Treatment of Rotator Cuff Tears with Bone Marrow Concentrate and Platelet Products Compared to Exercise Therapy: A Midterm Analysis. Stem Cells Int. 2020;2020:5962354. Published 2020 Jan 30. doi:10.1155/2020/5962354
  • 7. Centeno CJ, Pitts JA, Al-Sayegh H, Freeman MD (2014) Efficacy and Safety of Bone Marrow Concentrate for Osteoarthritisof the Hip; Treatment Registry Results for 196 Patients. J Stem Cell Res Ther 4: 242. doi:10.4172/2157-7633.1000242
  • 8. Darrow M, Shaw B, Darrow B, Wisz S. Short-Term Outcomes of Treatment of Hip Osteoarthritis With 4 Bone Marrow Concentrate Injections: A Case Series. Clin Med Insights Case Rep. 2018;11:1179547618791574. Published 2018 Aug 10. doi:10.1177/1179547618791574
  • 9. Centeno CJ, Al-Sayegh H, Bashir J, Goodyear S, Freeman MD. A prospective multi-site registry study of a specific protocol of autologous bone marrow concentrate for the treatment of shoulder rotator cuff tears and osteoarthritis. J Pain Res. 2015;8:269-276. Published 2015 Jun 5. doi:10.2147/JPR.S80872
  • 10. Singh A, Gangwar DS, Singh S. Bone marrow injection: A novel treatment for tennis elbow. J Nat Sci Biol Med. 2014;5(2):389-391. doi:10.4103/0976-9668.136198
  • 11. Lin, Junhong. International Journal of Clinical Pharmacology and Therapeutics; Munich Vol. 56, Iss. 8, (Aug 2018): 366.
  • 12. Kothari SY, Srikumar V, Singh N. Comparative Efficacy of Platelet Rich Plasma Injection, Corticosteroid Injection and Ultrasonic Therapy in the Treatment of Periarthritis Shoulder. J Clin Diagn Res. 2017;11(5):RC15-RC18. doi:10.7860/JCDR/2017/17060.9895
  • 13. Peerbooms JC, (2010) Positive effect of an autologous platelet concentrate in lateral epicondylitis in a double-blind randomized controlled trial: platelet-rich plasma versus corticosteroid injection with a 1-Year follow-up. http://www.ncbi.nlm.nih.gov/pubmed/20448192
  • 14. Gosens T, et al. (2011) Ongoing positive effect of platelet-rich plasma versus corticosteroid injection in lateral epicondylitis: a double-blind randomized controlled trial with 2-year follow-up. http://www.ncbi.nlm.nih.gov/pubmed/21422467
  • 15. Mishra A, et al. (2014) Efficacy of platelet-rich plasma for chronic tennis elbow: a double-blind, prospective, multicenter, randomized controlled trial of 230 patients. http://www.ncbi.nlm.nih.gov/pubmed/23825183
  • 16. Sanchez M, et al. (2007) Comparison of surgically repaired Achilles tendon tears using platelet rich fibrin matrices. http://www.ncbi.nlm.nih.gov/pubmed/17099241
  • 17. Dragoo JL, Wasterlain AS, Braun HJ, Nead KT. Platelet-Rich Plasma as a Treatment for Patellar Tendinopathy: A Double-Blind, Randomized Controlled Trial. The American Journal of Sports Medicine. 2014;42(3):610-618. doi:10.1177/0363546513518416
  • 18. Akşahin, Ertuğrul, et al. “The comparison of the effect of corticosteroids and platelet-rich plasma (PRP) for the treatment of plantar fasciitis.” Archives of orthopaedic and trauma surgery 132.6 (2012): 781-785.
  • 19. Ragab, Ehab Mohamed Selem, and Ahmed Mohamed Ahmed Othman. “Platelets rich plasma for treatment of chronic plantar fasciitis.” Archives of orthopaedic and trauma surgery 132.8 (2012): 1065-1070.
  • 20. Doaa H. Ibrahim, Nagat M. El-Gazzar, Hanan M. El-Saadany, Radwa M. El-Khouly, Ultrasound-guided injection of platelet rich plasma versus corticosteroid for treatment of rotator cuff tendinopathy: Effect on shoulder pain, disability, range of motion and ultrasonographic findings. The Egyptian Rheumatologist, Volume 41, Issue 2, 2019, Pages 157-161, ISSN 1110-1164, https://doi.org/10.1016/j.ejr.2018.06.004.
  • 21. Dadgostar, H., Fahimipour, F., Pahlevan Sabagh, A. et al. Corticosteroids or platelet-rich plasma injections for rotator cuff tendinopathy: a randomized clinical trial study. J Orthop Surg Res 16, 333 (2021). https://doi.org/10.1186/s13018-021-02470-x
  • 22. Begkas D, Chatzopoulos ST, Touzopoulos P, Balanika A, Pastroudis A. Ultrasound-guided Platelet-rich Plasma Application Versus Corticosteroid Injections for the Treatment of Greater Trochanteric Pain Syndrome: A Prospective Controlled Randomized Comparative Clinical Study. Cureus. 2020;12(1):e6583. Published 2020 Jan 7. doi:10.7759/cureus.6583
  • 23. ROSÁRIO, DAVI ARAÚJO VEIGA et al. COMPARISON BETWEEN CONCENTRATED BONE MARROW ASPIRATE AND CORTICOID IN GLUTEAL TENDINOPATHY. Acta Ortopédica Brasileira [online]. 2021, v. 29, n. 1 [Accessed 1 December 2021] , pp. 26-29. Available from: <https://doi.org/10.1590/1413-785220212901236828>. Epub 10 Mar 2021. ISSN 1809-4406. https://doi.org/10.1590/1413-785220212901236828.
  • 24. Tang, J.Z., Nie, M.J., Zhao, J.Z. et al. Platelet-rich plasma versus hyaluronic acid in the treatment of knee osteoarthritis: a meta-analysis. J Orthop Surg Res 15, 403 (2020). https://doi.org/10.1186/s13018-020-01919-9